In Heart Transplant Patients, Vaccination Reduces Severe COVID-19 Risk



According to a research published online April 27 in JAMA Cardiology, COVID-19 immunisation is linked to reduced COVID-19 infections, hospitalizations, and fatalities among orthotopic heart transplant (OHT) patients, with no heart transplant-specific side effects.

Here are some COVID-19 vaccinations and fertility: What physicians wish patients knew. Read this article to know more.

Laura L. Peters, D.N.P., of the University of Colorado Anschutz Medical Campus in Aurora, and colleagues evaluated the safety and efficacy of COVID-19 immunisation in adult OHT patients using data from a single U.S. heart transplant programme.

The researchers discovered that 106 of the 436 OHT patients had COVID-19 infection. COVID-19 infections were found in 19.7% of the 366 vaccinated participants, 4.1 percent needed hospitalisation (including four ICU stays), and three patients died (0.8 percent). 48.6% of the 70 unvaccinated people were infected, 14.3% were admitted to the hospital, three needed ICU hospitalisation, and three died (4.3 percent). COVID-19 immunisation resulted in a decreased risk of all outcomes (risk ratios: infection, 0.41; hospitalization, 0.29; death, 0.19). There was no echocardiographic indication of graft malfunction, clinically severe rejection, or allosensitization six months following COVID-19 immunisation in the vaccinated OHT patients.


"Even though patients who receive a heart transplant have a lower immunogenic response to COVID-19 vaccination, the vaccine appears to be safe and is associated with a lower risk of COVID-19 infection, hospitalisation, and death, suggesting that all heart transplant recipients should get the COVID-19 vaccine," the authors write.

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